rG(dmf) Phosphoramidite (CAS NO. 149559-87-5) is a modified building block commonly used in the solid-phase synthesis of RNA oligonucleotides. It is a guanosine nucleoside modified with a tert-butyldimethylsilyl (TBDMS) group protecting the 3'-OH group and an dmf group protecting the N2 position. The phosphoramidite group is attached to the 2'-OH position of the nucleoside.
To achieve excellent quality and dependability, 2'-TBDMS-rG(dmf) Phosphoramidite, commonly known as ibu-rG Phosphoramidite, is manufactured using regulated procedures. Its CAS number 149559-87-5 and product code HR-00202015 make it appropriate for oligonucleotide synthesis, particularly when stability and nuclease activity resistance are required. It may be utilized in a variety of nucleic acid-based applications, including gene design, genome editing, antisense oligonucleotides, and siRNA, as well as CRISPR-cas9 gRNA.
| Product | CAS NO. | Product Code | Molecular Formula | Molecular Weight | Purity | Appearance | Storage Conditions | water |
| 2'-TBDMS-rG(dmf) Phosphoramidite | 149559-87-5 | HR-00202015 | C49H67N8O8PSi | 955.18 | ≥98% | White to light yellow powder | -20℃ | ≤0.5% |